DUSP3 CLIA Kit for Human(Homo sapiens) | EIAab.comDUSP3 CLIA Kit for Human(Homo sapiens)

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Index > Protein center > DUSP3(Gene name) > Human

DUSP3 (Gene name),

Dual specificity protein phosphatase 3 (Protein name ), DUS3_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

DUSP3(VHR);

Protein name:

Dual specificity protein phosphatase 3;

Alternative:

Vaccinia H1-related phosphatase(VHR);Dual specificity protein phosphatase VHR;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with VRK3, which seems to activate it's phosphatase activity.

Function:

Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

185

Sequence:

50:

100:

150:

185:

LSIVRQNREI | GPNDGFLAQL | CQLNDRLAKE | GKLKP

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.181046

MIM:

600183

String:

P51452

KEGG:

hsa:1845

SMR:

P51452

Pfam:

PF00782

STRING:

9606.ENSP00000226004

Uniprot:

P51452

FOR

ELISA Kit for Human Dual specificity protein phosphatase 3

Cat.:

E12249m

Price:

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Packing:

96T

ELISA Kit for Human Dual specificity protein phosphatase 3

Cat.:

E12249h

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Manual:

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Packing:

96T

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CLIA Kit for Human Dual specificity protein phosphatase 3

Cat.:

U12249h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Dual specificity protein phosphatase 3

Cat.:

U12249m

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Dual specificity protein phosphatase 3

Cat.:

P12249Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Dual specificity protein phosphatase 3

Protein for Human Dual specificity protein phosphatase 3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Expression cloning of a human dual-specificity phosphatase."
Ishibashi T. , Bottaro D.P. , Chan A. , Miki T. , Aaronson S.A.
Proc. Natl. Acad. Sci. U.S.A.89:12170-12174(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
2.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2004-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
3.

"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
Zody M.C. , Garber M. , Adams D.J. , Sharpe T. , Harrow J. , Lupski J.R. , Nicholson C. , Searle S.M. , Wilming L. , Young S.K. , Abouelleil A. , Allen N.R. , Bi W. , Bloom T. , Borowsky M.L. , Bugalter B.E. , Butler J. , Chang J.L. , more...
Nature440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
tissue: Duodenum.
tissue: Uterus.
6.

"Extracellular regulated kinases (ERK) 1 and ERK2 are authentic substrates for the dual-specificity protein-tyrosine phosphatase VHR. A novel role in down-regulating the ERK pathway."
Todd J.L. , Tanner K.G. , Denu J.M.
J. Biol. Chem.274:13271-13280(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
7.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
8.

"Crystal structure of the dual specificity protein phosphatase VHR."
Yuvaniyama J. , Denu J.M. , Dixon J.E. , Saper M.A.
Science272:1328-1331(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS)
9.

"Structural basis for the recognition of a bisphosphorylated MAP kinase peptide by human VHR protein Phosphatase."
Schumacher M.A. , Todd J.L. , Rice A.E. , Tanner K.G. , Denu J.M.
Biochemistry41:3009-3017(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.75 ANGSTROMS) OF 2-185;FUNCTION
10.

"Multidentate small-molecule inhibitors of vaccinia H1-related (VHR) phosphatase decrease proliferation of cervix cancer cells."
Wu S. , Vossius S. , Rahmouni S. , Miletic A.V. , Vang T. , Vazquez-Rodriguez J. , Cerignoli F. , Arimura Y. , Williams S. , Hayes T. , Moutschen M. , Vasile S. , Pellecchia M. , Mustelin T. , Tautz L.
J. Med. Chem.52:6716-6723(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 3-185

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